![]() In these situations, ASA is used on an as-needed basis.īecause of the antiplatelet (anticlotting) properties of ASA, it may be used under the supervision of your doctor to: It works by interfering with the production of compounds in the body that cause pain, fever, inflammation, and blood clots.Īcetylsalicylic acid (ASA) is used to relieve pain, fever, and inflammation in various conditions such as lower back and neck pain, the flu, common cold, burns, menstrual pain, headache, migraines, osteoarthritis, rheumatoid arthritis, sprains and strains, nerve pain, toothache, muscle pain, bursitis (inflammation of a bursa, a fluid-filled sac located around joints and near the bones), and following surgical and dental procedures. Anise, arnica, cayenne, chamomile, clove, fenugreek, feverfew, garlic, ginger, ginkgo biloba, ginseng, horse chestnut, kelpware, licorice: increased bleeding riskĭrug-behaviors.How does this medication work? What will it do for me?Īcetylsalicylic acid (ASA) belongs to the groups of medications called analgesics (pain relievers), antipyretics (fever reducers), anti-inflammatories (inflammation reducers), and platelet aggregation inhibitors (anticlotting agents). Urine-acidifying foods: increased salicylate blood levelĭrug-herbs. Tests using phenosulfonphthalein as diagnostic agent: decreased urinary excretion of phenosulfonphthalein Urine protein: increased levelĭrug-food. Pregnancy test, protirelin-induced thyroid stimulating hormone, radionuclide thyroid imaging, serum theophylline (Schack and Waxler method), urine catecholamines, urine glucose, urine hydroxyindoleacetic acid, urine ketones (ferric chloride method), urine vanillylmandelic acid: test interference Alanine aminotransferase, alkaline phosphatase, amylase, aspartate aminotransferase, coagulation studies, PaCO 2, uric acid: increased valuesĬholesterol, glucose, potassium, protein-bound iodine, sodium, thyroxine, tri-iodothyronine: decreased levels Tetracycline (oral): decreased absorption of tetracycline (with buffered aspirin)ĭrug-diagnostic tests. Sulfonylureas (such as chlorpropamide, tolbutamide): enhanced sulfonylurea effects Spironolactone: decreased spironolactone effect Methotrexate: decreased methotrexate excretion and increased blood level, causing greater risk of toxicity Nizatidine: increased salicylate blood level Acidifying drugs (such as ammonium chloride): increased salicylate blood levelĪctivated charcoal: decreased salicylate absorptionĪlkalinizing drugs (such as antacids): decreased salicylate blood level Angiotensin-converting enzyme (ACE) inhibitors: decreased antihypertensive effectĪnticoagulants, NSAIDs, thrombolytics: increased bleeding riskĬarbonic anhydrase inhibitors (such as acetazolamide): salicylismĬorticosteroids: increased salicylate excretion and decreased blood level Furosemide: increased diuretic effect Live varicella virus vaccine: increased risk of Reye's syndrome Maintenance dosage is 3 to 10 mg/kg/day given as a single dose for up to 8 weeks or until platelet count and erythrocyte sedimentation rate return to normal.Īdults: 325 to 650 mg P.O. ➣ To reduce the risk of myocardial infarction (MI) in patients with a history of MI or unstable anginaĬhildren: Initially during acute febrile period, 80 to 180 mg/kg/day P.O. ![]() ➣ To reduce the risk of transient ischemic attacks (TIAs) or cerebrovascular accident in men with a history of TIAs caused by emboliĪdults: 650 mg P.O. in individual doses for first 2 weeks then maintenance dosage of 75 mg/kg/day P.O. in divided dosesĬhildren: Initially, 100 mg/kg/day P.O. give in divided doses q 6 to 8 hours.Īdults: 5 to 8 g/day P.O. daily in children weighing more than 25 kg P.O. in children weighing 25 kg (55 lb) or less, or 2,400 to 3,600 mg P.O. in divided doses, to a maximum dosage of 6 g/day.Ĭhildren: 60 to 130 mg/kg/day P.O. Usual maintenance dosage is 3.6 to 5.4 g/day P.O. Dosage may be increased by 325 to 1,200 mg daily at intervals of at least 1 week. ➣ Mild to moderate pain caused by inflammation (as in rheumatoid arthritis or osteoarthritis)Īdults: Initially, 2,400 to 3,600 mg P.O.
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